NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell and plays a critical role in energy production, DNA repair, and many processes that determine how we age. NAD+ levels decline with age — dropping by as much as 50% between young adulthood and midlife and this decline is closely linked to many of the hallmarks of aging: fatigue, cognitive fog, slower recovery, metabolic slowdown, and reduced cellular resilience.
NAD+ therapy delivers this critical molecule directly into the bloodstream for rapid absorption that oral supplements simply can’t achieve.
NAD+ powers the mitochondria leading to more efficient ATP production and real, sustained energy. It activates sirtuins, sometimes called “longevity genes,” which regulate inflammation, repair damaged DNA, and influence how cells respond to metabolic stress. It supports PARP enzymes that detect and repair DNA strand breaks and plays a central role in autophagy — the cellular cleanup process that clears damaged components and recycles them. Autophagy is now understood to be foundational to both longevity and metabolic health.
The gold-standard delivery method. A therapeutic dose is administered slowly over one to four hours, delivering NAD+ directly to cells at concentrations impossible to achieve orally. Patients commonly report noticeably improved mental clarity and focus during and after the infusion — many describe it as a “cognitive reset.” Energy improvements often persist for weeks with a consistent protocol. IV NAD+ is also increasingly integrated into neurological recovery protocols, given NAD+’s role in neuroprotection and healthy neurotransmitter function.
For patients seeking a faster, more convenient option — or looking to maintain elevated levels between IV sessions — intramuscular injections offer an effective and practical alternative. Administered in minutes rather than hours, they’re ideal for regular maintenance dosing. Bioavailability is meaningfully superior to oral supplements, even if the dose is smaller than an IV infusion.
NAD+ therapy is well-suited for patients seeking mental clarity, focus, and cognitive performance; sustained energy and reduced fatigue; athletic recovery and performance optimization; healthy aging and longevity protocols; metabolic support; recovery from burnout, prolonged illness, or chronic stress; and neurological wellness and mood support.
A series of 2–4 initial IV infusions is typically recommended to build cellular NAD+ levels, followed by maintenance injections or periodic IV boosters. Our team works with each patient to design a protocol that fits their goals, lifestyle, and budget.
